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Pf-06726304 is an effective selective EZH2 inhibitor. Pf-06726304 inhibited wild type and Y641N mutant EZH2 with Ki of 0.7 and 3.0 nM, respectively. Pf-06726304 has strong anti-tumor growth activity.
| Molecular Weight | 446.33 |
| Formula | C22H21Cl2N3O3 |
| CAS Number | 1616287-82-1 |
| Solubility (25°C) | DMSO ≥ 5 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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