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PF-06648671 

Cat. No. M28634

All AbMole products are for research use only, cannot be used for human consumption.

PF-06648671  Structure

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Quality Control & Documentation
Biological Activity

PF-06648671 is a novel, brain-penetrable, and orally active γ-secretase modulator (GSM). PF-06648671 reduces Aβ42 and Aβ40, with concomitant increases in Aβ37 and Aβ38 in vitro. PF-06648671 is used for the study of Alzheimer’s disease.

Chemical Information
Molecular Weight 538.92
Formula C25H23ClF4N4O3
CAS Number 1587727-31-8
Form Solid
Storage Powder -20°C
References

[1] Jae Eun Ahn, et al. Clin Pharmacol Ther. Pharmacokinetic and Pharmacodynamic Effects of a γ-Secretase Modulator, PF-06648671, on CSF Amyloid-β Peptides in Randomized Phase I Studies

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  Catalog
Abmole Inhibitor Catalog




Keywords: PF-06648671  supplier, Gamma-secretase/Beta-secretase, inhibitors, activators

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