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PF-05186462 is a potent and selective inhibitor of human Nav1.7 voltage-dependent sodium channel, with an IC50 of 21 nM. PF-05186462 shows significant selectivity for Nav1.7 versus other sodium channels (Nav 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, and 1.8). PF-05186462 can be used for the research of acute or chronic pain.
| Molecular Weight | 531.89 |
| Formula | C19H10ClF4N5O3S2 |
| CAS Number | 1235406-03-7 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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