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PF 04449613

Cat. No. M7114

All AbMole products are for research use only, cannot be used for human consumption.

PF 04449613 Structure

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Quality Control & Documentation
Biological Activity

PF 04449613 is a potent PDE9 inhibitor (IC50 = 22 nM). Also exhibits a high affinity for cGMP (Km ~170 nM). Brain penetrant.

Chemical Information
Molecular Weight 395.45
Formula C21H25N5O3
CAS Number 1236858-52-8
Solubility (25°C) 1eq. HCl 3.95 mg/mL (with gentle warming)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Larrieu, et al. Science. Chemical inhibition of NAT10 corrects defects of laminopathic cells.

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  Catalog
Abmole Inhibitor Catalog




Keywords: PF 04449613 supplier, inhibitors, activators

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