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PF-02413873 is a potent, selective and fully competitive non-steroidal progesterone receptor (PR) antagonist that blocks progesterone binding and PR nuclear translocation. PF-02413873 suppresses endometrial growth in the macaque and human.
| Molecular Weight | 359.44 |
| Formula | C18H21N3O3S |
| CAS Number | 936345-35-6 |
| Solubility (25°C) | DMSO: 2 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Hannah M Jones, et al. Application of PBPK modelling in drug discovery and development at Pfizer
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