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Petosemtamab (MCLA 158) is an anti- EGFR (Kd: 0.22 nM) and anti-LGR5 (Kd: 0.86 nM) monoclonal antibody (mAb). Petosemtamab leads to EGFR signaling blockade and receptor degradation in LGR5+ cancer cells. Petosemtamab can be used in the research of solid tumors, such as head and neck squamous cell carcinoma (HNSCC), metastatic colorectal cancer (CRC).
| CAS Number | 2213450-26-9 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Products are for research use only. Not for human use. We do not sell to patients.
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