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Perospirone

Cat. No. M20987

All AbMole products are for research use only, cannot be used for human consumption.

Perospirone Structure
Synonym:

SM-9018 free base

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Quality Control & Documentation
Biological Activity

Perospirone (SM-9018 free base) is an orally active antagonist of 5-hydroxytryptamine2 (5-HT2) receptor, dopamine2 (D2) receptor and 5-HT1A receptor with Ki of 0.6 nM, 1.4 nM and 2.9 nM, respectively.

Chemical Information
Molecular Weight 426.57
Formula C23H30N4O2S
CAS Number 150915-41-6
Solubility (25°C) DMSO 85 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yasunori Haranishi, et al. Pharmacol Biochem Behav. Antihyperalgesic effects of intrathecal perospirone in a rat model of neuropathic pain

[2] Taro Kishi, et al. CNS Drugs. Efficacy and tolerability of perospirone in schizophrenia: a systematic review and meta-analysis of randomized controlled trials

[3] Tomas de Paulis. Curr Opin Investig Drugs. Perospirone (Sumitomo Pharmaceuticals)

[4] S V Onrust, et al. CNS Drugs. Perospirone

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Keywords: Perospirone, SM-9018 free base supplier, 5-HT Receptor, inhibitors, activators

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