Free shipping on all orders over $ 500

Perospirone hydrochloride

Cat. No. M20437

All AbMole products are for research use only, cannot be used for human consumption.

Perospirone hydrochloride Structure
Synonym:

SM-9018 hydrochloride

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

Perospirone is an atypical or second-generation antipsychotic of the azapirone family that antagonizes serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.

Chemical Information
Molecular Weight 463.04
Formula C23H31ClN4O2S
CAS Number 129273-38-7
Solubility (25°C) DMSO 92 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Ning Ma, et al. J Chromatogr B Analyt Technol Biomed Life Sci. Determination of perospirone by liquid chromatography/electrospray mass spectrometry: application to a pharmacokinetic study in healthy Chinese volunteers

[2] Tsuguka Shiwa, et al. J Pharmacol Sci. Perospirone, a novel antipsychotic agent, hyperpolarizes rat dorsal raphe neurons via 5-HT1A receptor

[3] Y Ohno. Nihon Yakurigaku Zasshi. [Pharmacological characteristics of perospirone hydrochloride, a novel antipsychotic agent]

[4] H Yu, et al. Jpn J Pharmacol. Effects of perospirone, a novel antipsychotic agent, on the dopaminergic neurons in the rat ventral tegmental area

Related 5-HT Receptor Products
Granisetron hydrochloride

Granisetron hydrochloride is a potent and selective 5-HT3 receptor antagonist that possesses potent antiemetic activity.

Sumatriptan succinate

Sumatriptan succinate (GR 43175) is an orally active 5-HT1 receptor agonist with Kis of 17 nM, 27 nM and 100 nM for 5-HT1D, 5-HT1B and 5-HT1A receptors, respectively. Sumatriptan succinate can be used for the research of migraine headache.

Vortioxetine hydrobromide

Vortioxetine hydrobromide (Lu AA21004) is a 5-HT3, 5-HT7 and 5-HT1D receptor antagonist, a 5-HT1B receptor partial agonist, a 5-HT1A receptor agonist and a 5-HT transporter (5-HTT) inhibitor in vitro.

Prucalopride

Prucalopride is a potent, selective and specific serotonin 5-HT4 receptor agonist with enterokinetic properties.

(1S-cis)-Milnacipran Hydrochloride

(1S-cis)-Milnacipran hydrochloride is a selective norepinephrine and serotonin reuptake inhibitor approved for the management of fibromyalgia.

  Catalog
Abmole Inhibitor Catalog




Keywords: Perospirone hydrochloride, SM-9018 hydrochloride supplier, 5-HT Receptor, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.