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Perindopril Erbumine is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor.
| Cell Experiment | |
|---|---|
| Cell lines | |
| Preparation method | |
| Concentrations | |
| Incubation time | |
| Animal Experiment | |
|---|---|
| Animal models | Female BALB/c nude mice injected with SCC-VII cells |
| Formulation | Dissolved in DMSO, and diluted in saline |
| Dosages | 1 or 2 mg/kg/day |
| Administration | Orally |
| Molecular Weight | 441.6 |
| Formula | C19H32N2O5.C4H11N |
| CAS Number | 107133-36-8 |
| Form | Solid |
| Solubility (25°C) | Water 80 mg/mL Ethanol 80 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Matt Shirley, et al. Perindopril/amlodipine (Prestalia(®)): a review in hypertension
[5] No authors listed. Am J Health Syst Pharm. Perindopril erbumine
| Related ACE Products |
|---|
| Temocapril
Temocapril is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension. |
| Enalaprilat Dihydrate
Enalaprilat is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM. |
| Imidapril hydrochloride
Imidapril hydrochloride is a angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension. |
| Ramipril
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM. |
| Enalapril Maleate
Enalapril Maleate, the active metabolite of enalapril, competes with angiotensin I for binding at the angiotensin-converting enzyme, blocking the conversion of angiotensin I to angiotensin II. |
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