Free shipping on all orders over $ 500

Pepinemab

Cat. No. M24915

All AbMole products are for research use only, cannot be used for human consumption.

Pepinemab Structure
Synonym:

VX 15/2503

Size Price Availability Quantity
100ug USD 150 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D.

Chemical Information
CAS Number 2097151-87-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Andrew Feigin, et al. Nat Med. Publisher Correction: Pepinemab antibody blockade of SEMA4D in early Huntington's disease: a randomized, placebo-controlled, phase 2 trial

[2] Andrew Feigin, et al. Nat Med. Pepinemab antibody blockade of SEMA4D in early Huntington's disease: a randomized, placebo-controlled, phase 2 trial

[3] Michael R Shafique, et al. Clin Cancer Res. A Phase Ib/II Study of Pepinemab in Combination with Avelumab in Advanced Non-Small Cell Lung Cancer

Related Products
Lactate calcium

Lactate calcium is an excellent calcium fortifier that works better than inorganic calcium. Lactate calcium is used as an antacid.

Coniferyl ferulate

Coniferyl ferulate is a potent glutathione S-transferase (GST) inhibitor that reverses multidrug resistance and down-regulates p-glycoprotein. Coniferyl ferulate strongly inhibited human placental glutathione S-transferase with IC50 of 0.3 μM.

NXY-059

NXY-059 is a free radical-trapping neuroprotectant that has been reported to reduce infarct size and preserve brain function in experimental models of acute ischemic stroke.

Tie2 kinase inhibitor

Tie2 kinase inhibitor is a potent, reversible, and ATP-binding site-targeting Tie2 inhibitor with an IC50 of 250 nM.

Calcium levofolinate

Calcium levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.

  Catalog
Abmole Inhibitor Catalog




Keywords: Pepinemab, VX 15/2503 supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.