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Pentamidine

Cat. No. M27605

All AbMole products are for research use only, cannot be used for human consumption.

Pentamidine Structure
Synonym:

MP-601205

Size Price Availability Quantity
50mg USD 50 In stock
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Quality Control & Documentation
Biological Activity

Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.

Chemical Information
Molecular Weight 340.42
Formula C19H24N4O2
CAS Number 100-33-4
Solubility (25°C) Soluble in DMSO
Storage -20°C, dry, sealed
References

[1] Bo Zhang, et al. Curr Med Chem. Ninety Years of Pentamidine: The Development and Applications of Pentamidine and its Analogs

[2] R M Sieve, et al. J Pediatr Oncol Nurs. Pentamidine

[3] M Sands, et al. Rev Infect Dis. Pentamidine: a review

[4] B Gazzard. Br J Clin Pract. Pentamidine

[5] B Wispelwey, et al. Infect Control Hosp Epidemiol. Pentamidine: a review

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Keywords: Pentamidine, MP-601205 supplier, Parasite, inhibitors, activators

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