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Penfluridol (R-16341) effectively inhibits TNFα-induced NF-κB activation and alleviates the severity of arthritis and colitis in vivo. Penfluridol is a Ca2+-calmodulin inhibitor. Penfluridol induces apoptosis and autophagy.
| Molecular Weight | 523.97 |
| Formula | C28H27ClF5NO |
| CAS Number | 26864-56-2 |
| Form | Solid |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Nguyen Minh Tuan, et al. Penfluridol as a Candidate of Drug Repurposing for Anticancer Agent
[3] Jacqueline Pich. Review: Chlorpromazine Versus Penfluridol for Schizophrenia
[4] Naemeh Nikvarz, et al. Chlorpromazine versus penfluridol for schizophrenia
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