All AbMole products are for research use only, cannot be used for human consumption.
BMS-1 (PD-1/PD-L1 inhibitor 1, PD1-PDL1-IN1) is an inhibitor of PD-1/PD-L1 protein/protein interaction with an IC50 of 6 to 100 nM.
Cell Death Discov. 2023 Jun 30;9(1):205.
RNF8 enhances the sensitivity of PD-L1 inhibitor against melanoma through ubiquitination of galectin-3 in stroma
BMS-1 (PD-1/PD-L1 inhibitor 1, PD1-PDL1-IN1) purchased from AbMole
J Cancer Res Clin Oncol. 2023 Feb 6.
Carbon ion irradiation induces DNA damage in melanoma and optimizes the tumor microenvironment based on the cGAS–STING pathway
BMS-1 (PD-1/PD-L1 inhibitor 1, PD1-PDL1-IN1) purchased from AbMole
J Allergy Clin Immunol. 2020 Mar;145(3):855-867.e8.
Effects of myeloid and plasmacytoid dendritic cells on ILC2s in patients with allergic rhinitis.
BMS-1 (PD-1/PD-L1 inhibitor 1, PD1-PDL1-IN1) purchased from AbMole
| Molecular Weight | 475.58 |
| Formula | C29H33NO5 |
| CAS Number | 1675201-83-8 |
| Solubility (25°C) | DMSO: ≥ 60 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Tsukahara T, et al. Expert Opin Biol Ther. The future of immunotherapy for sarcoma.
| Related PD-1/PD-L1 Products |
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| Avelumab (MSB0010718C)
Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). Avelumab recognizes murine PD-L1 |
| Panaxadiol
Panaxadiol exists in ginseng root and has neuroprotective and anti-tumor functions. Panaxadiol inhibits the expression of programmed cell death ligand-1 (PD-L1) and tumor proliferation. |
| Fraxinellone
Fraxinellone was isolated from the root bark of the brassica family Dictamnus dasycarpus. Fraxinellone is a PD-L1 inhibitor that inhibits HIF-1α synthesis without affecting HIF-1α degradation. Fraxinellone has potential for cancer immunity by targeting PD-L1. |
| BMS202
Bms-202 is an effective non-peptide PD-1/PD-L complex inhibitor with IC50 of 18 nM and KD of 8 μM. Bms-202 directly binds to PD-L1 and blocks the human PD-1/PD-L interaction. Bms-202 has antitumor activity. |
| Sulfamethoxypyridazine
Sulfamethoxypyridazine is a long-acting sulfonamide for treatment of Dermatitis herpetiformis. |
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Products are for research use only. Not for human use. We do not sell to patients.
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