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PD-1/PD-L1-IN-10 

Cat. No. M29673

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PD-1/PD-L1-IN-10  Structure

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Quality Control & Documentation
Biological Activity

PD-1/PD-L1-IN-10 (compound B2) is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.

Chemical Information
Molecular Weight 581.62
Formula C33H31N3O7
CAS Number 2487550-41-2
Form Solid
Solubility (25°C) DMSO 100 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yunzhou Pu, et al. Front Immunol. Tumor-Associated Macrophages Regulate PD-1/PD-L1 Immunosuppression

[2] Chinmoy Ghosh, et al. J Cancer. A snapshot of the PD-1/PD-L1 pathway

[3] Yanyan Han, et al. Am J Cancer Res. PD-1/PD-L1 pathway: current researches in cancer

[4] Nyanbol Kuol, et al. Immunotherapy. PD-1/PD-L1 in disease

[5] Xinxin Zhu, et al. Oncotarget. Soluble PD-1 and PD-L1: predictive and prognostic significance in cancer

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  Catalog
Abmole Inhibitor Catalog




Keywords: PD-1/PD-L1-IN-10  supplier, PD-1/PD-L1, inhibitors, activators

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