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Pantoprazole sodium hydrate (BY10232 sodium hydrate) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole sodium hydrate is also a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium hydrate improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium hydrate significantly increased tumor growth delay combined with Doxorubicin .
| Molecular Weight | 432.37 |
| Formula | C16H17F2N3NaO5.5S |
| CAS Number | 164579-32-2 |
| Solubility (25°C) | Water > 150 mg/mL DMSO 90 mg/mL |
| Storage | 2-8°C, protect from light, dry, sealed |
[1] Chen Bei, et al. [Characterization and stability of S (-) pantoprazole sodium hydrates]
[3] V Zupancic, et al. Physical characterization of pantoprazole sodium hydrates
| Related Proton Pump Products |
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Omeprazol is a first-in-class proton pump inhibitor (PPI) used in the treatment of dyspepsia, laryngopharyngeal reflux (LPR) and Zollinger–Ellison syndrome. |
| Dexlansoprazole
Dexlansoprazole, the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties. |
| Tenatoprazole
Tenatoprazole is a procompound of the proton pump inhibitor (PPI) class, which inhibits proton transport with IC50 of 3.2 μM. |
| Esomeprazole Sodium
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| Esomeprazole Magnesium
Esomeprazole Magnesium is a proton pump inhibitor to reduce gastric acid secretion. |
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