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Pancuronium dibromide

Cat. No. M3534

All AbMole products are for research use only, cannot be used for human consumption.

Pancuronium dibromide Structure
Size Price Availability Quantity
10mg USD 50 In stock
50mg USD 140 In stock
100mg USD 250 In stock
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Quality Control & Documentation
Biological Activity

Pancuronium (Pavulon) is a competitive acetylcholine antagonist with an IC50 of 5.5 ?0.5 nM.It is a typical non-depolarizing curare-mimetic muscle relaxant. It acts as a competitive acetylcholine antagonist on neuromuscular junctions, displacing acetylcholine (hence competitive) from its post-synaptic nicotinic acetylcholine receptors. It is (unlike suxamethonium) a non-depolarizing agent, which means that it causes no spontaneous depolarizations upon association with the nicotinic receptor in neuromuscular junction, thus producing no muscle fasciculations upon administration.

Chemical Information
Molecular Weight 732.67
Formula C35H60N2O4.2Br
CAS Number 15500-66-0
Solubility (25°C) DMSO 90 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Lauren V Cairns, et al. Multiplex Screening for Interacting Compounds in Paediatric Acute Myeloid Leukaemia

[2] No authors listed. Pancuronium

[3] Shoichi Okada, et al. Tugging force: A new objective index for evaluating acute changes in neuromuscular function in mice

[4] S G Solomon, et al. Neurokinin-1 receptors and spinal cord control of blood pressure in spontaneously hypertensive rats

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Keywords: Pancuronium dibromide supplier, AChR/AChE, inhibitors, activators

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