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Pamoic acid disodium

Cat. No. M10597

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Pamoic acid disodium Structure
Size Price Availability Quantity
10mg USD 35 In stock
50mg USD 70 In stock
100mg USD 90 In stock
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Biological Activity

Pamoic acid disodium is a potent GPR35 agonist with an EC50 value of 79 nM. Pamoic acid disodium induces GPR35 internalization and activates ERK1/2 with EC50 values of 22 nM and 65 nM, respectively.

Chemical Information
Molecular Weight 432.33
Formula C23H14Na2O6
CAS Number 6640-22-8
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Pingwei Zhao, et al. Mol Pharmacol. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity

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Keywords: Pamoic acid disodium supplier, ERK, inhibitors, activators

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