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CB-5339 is a potent p97 inhibitor with an IC50 <30 nM (WO2015109285A1, compound FF07).
| Molecular Weight | 412.49 |
| Formula | C24H24N6O |
| CAS Number | 1863952-15-1 |
| Form | Solid |
| Solubility (25°C) | DMSO 41.67 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage | Powder -20°C |
| Related p97 Products |
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| NMS-873
NMS-873 is a potent, selective allosteric VCP/p97 inhibitor with an IC50 value of 30 nM. |
| DBeQ
DBeQ is a selective, potent, reversible, and ATP-competitive p97 inhibitor with IC50 of 1.5 μM. |
| CB-5083
CB-5083 is a first-in-class, potent and selective, orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM. |
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