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P32/98 

Cat. No. M28256

All AbMole products are for research use only, cannot be used for human consumption.

P32/98  Structure

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Quality Control & Documentation
Biological Activity

P32/98 a potent inhibitor of dipeptidyl peptidase IV with a Ki value of 130 nM. P32/98 improves glucose tolerance, insulin sensitivity and β-cell responsiveness in fatty Zucker rat model.

Chemical Information
Molecular Weight 202.32
Formula C9H18N2OS
CAS Number 136259-20-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Bao-Sheng Yu, et al. World J Pediatr. Glucagon-like peptide 1 based therapy for type 2 diabetes

[2] P Augstein, et al. Diabetes Obes Metab. Efficacy of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide (P32/98) in fatty Zucker rats with incipient and manifest impaired glucose tolerance

[3] E Wargent, et al. Diabetes Obes Metab. Improvement of glucose tolerance in Zucker diabetic fatty rats by long-term treatment with the dipeptidyl peptidase inhibitor P32/98: comparison with and combination with rosiglitazone

[4] Antje Meyer, et al. J Chromatogr B Analyt Technol Biomed Life Sci. Quantitative analysis of dipeptidyl peptidase inhibitor P32/98 and its main metabolite in rat, dog, mouse, monkey, human plasma and human urine using liquid chromatography-tandem mass spectrometry: application to pharmacokinetic evaluation

[5] J A Pospisilik, et al. Diabetes. Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats

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  Catalog
Abmole Inhibitor Catalog




Keywords: P32/98  supplier, Dipeptidyl Peptidase, inhibitors, activators

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