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Sarecycline hydrochloride

Cat. No. M2549

All AbMole products are for research use only, cannot be used for human consumption.

Sarecycline hydrochloride Structure
Synonym:

P005672 hydrochloride

Size Price Availability Quantity
1mg USD 100 In stock
5mg USD 160 In stock
10mg USD 260 In stock
25mg USD 480 In stock
50mg USD 680 In stock
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Quality Control & Documentation
Biological Activity

Sarecycline hydrochloride is an orally active narrow-spectrum tetracycline derivative antibiotic. Sarecycline hydrochloride has anti-inflammatory activity. Sarecycline hydrochloride inhibits the activity of Gram-positive bacteria and several types of keratobacterium acnes. Sarecycline hydrochloride interferes with tRNA accommodation and tethers mRNA to the 70S ribosome.

Chemical Information
Molecular Weight 523.96
Formula C24H29N3O8.HCl
CAS Number 1035979-44-2
Solubility (25°C) DMSO 60 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Christopher G Bunick, et al. Antibiotics (Basel). Antibacterial Mechanisms and Efficacy of Sarecycline in Animal Models of Infection and Inflammation

[2] Zahra Batool, et al. Proc Natl Acad Sci U S A. Sarecycline interferes with tRNA accommodation and tethers mRNA to the 70S ribosome

[3] George Zhanel, et al. Antimicrob Agents Chemother. Microbiological Profile of Sarecycline, a Novel Targeted Spectrum Tetracycline for the Treatment of Acne Vulgaris

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Keywords: Sarecycline hydrochloride, P005672 hydrochloride supplier, Antibiotic, inhibitors, activators

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