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Oxiconazole (Ro 13-8996) nitrate is a broad spectrum anti-fungal agent which can inhibit the growth of Candida, Aspergillus and Trichophyton. Oxiconazole nitrate is also a highly efficacious activator of CYP3A4 transactivation, which could be antagonized by Rifampicin in a competitive manner. Oxiconazole nitrate exhibits inhibitory effect against colorectal cancer (CRC) via peroxiredoxin-2 (PRDX2)-mediated autophagy arrest.
| Molecular Weight | 492.14 |
| Formula | C18H14Cl4N4O4 |
| CAS Number | 64211-46-7 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 100 mg/mL |
| Storage | 4°C, dry, sealed |
| Related Antifungal Products |
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| 2-Phenylethyl isothiocyanate
2-Phenylethyl isothiocyanate is a natural product found in bean sprouts and cruciferous vegetables, and is also an effective antifungal agent, significantly inhibiting spore germination and mycelial growth of Aspergillus intermedius. In addition, 2-Phenylethyl isothiocyanate induces autophagy and inhibits the growth of various tumor cells. |
| Mutanocyclin
Mutanocyclin, a tetramic acids analog, is also a potent antifungal agent that inhibits mycelium formation in Candida albicans. In addition, Mutanocyclin also reduces the mRNA expression of HWP1, ECE1, FLO8, TEC1, and has inhibitory activity against immune cell infiltration. |
| 2-O-Methylanigorufone
2-O-Methylanigorufone (Methoxyanigorufone) is a natural product which can be from Monochoria vaginalis or Musa acuminata. |
| Xanthoxylin
Xanthoxylin has antifungal and antispasmodic activities. Xanthoxylin is isolated from Zanthoxylum simulans. |
| 2-Hydroxy-1,4-naphoquinone
2-Hydroxy-1,4-naphoquinone |
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