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Oxfenicine

Cat. No. M39815

All AbMole products are for research use only, cannot be used for human consumption.

Oxfenicine Structure

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Quality Control & Documentation
Biological Activity

Oxfenicine (L-p-Hydroxyphenylglycine) is an orally active carnitine palmitoyltransferase-1 inhibitor. Oxfenicine inhibits the oxidation of fatty acid in heart. Oxfenicine protects heart from necrotic tissue damage during ischaemia.

Chemical Information
Molecular Weight 167.16
Formula C8H9NO3
CAS Number 32462-30-9
Form Solid
Solubility (25°C) Water 45 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Diane M Sepa-Kishi et al. Am J Physiol Regul Integr Comp Physiol. Antilipolytic and antilipogenic effects of the CPT-1b inhibitor oxfenicine in the white adipose tissue of rats

[2] Chih-Hsien Wang et al. PLoS One. Acetyl-l-carnitine and oxfenicine on cardiac pumping mechanics in streptozotocin-induced diabetes in male Wistar rats

[3] A J Higgins et al. Life Sci. Oxfenicine diverts rat muscle metabolism from fatty acid to carbohydrate oxidation and protects the ischaemic rat heart

[4] H Jodalen et al. J Mol Cell Cardiol. Oxfenicine-induced accumulation of lipid in the rat myocardium

[5] E Bachmann et al. Pharmacology. Biochemical mechanisms of oxfenicine cardiotoxicity

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Keywords: Oxfenicine supplier, inhibitors, activators

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