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OTS186935 

Cat. No. M29199

All AbMole products are for research use only, cannot be used for human consumption.

OTS186935  Structure

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Quality Control & Documentation
Biological Activity

OTS186935 is a potent protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. OTS186935 shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS193320 regulates the production of γ-H2AX in cancer cells.

Chemical Information
Molecular Weight 463.96
Formula C25H26ClN5O2
CAS Number 2093400-18-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Theodore Vougiouklakis, et al. Oncotarget. Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX

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  Catalog
Abmole Inhibitor Catalog




Keywords: OTS186935  supplier, Histone Methyltransferase, inhibitors, activators

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