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Oseltamivir phosphate

Cat. No. M3204

All AbMole products are for research use only, cannot be used for human consumption.

Oseltamivir phosphate Structure
Synonym:

GS 4104

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 55 In stock
100mg USD 40 In stock
500mg USD 100 In stock
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Quality Control & Documentation
Biological Activity

Oseltamivir phosphate (Tamiflu) is a competitive neuraminidase inhibitor. The prodrug oseltamivir phosphate (Tamiflu) is itself not virally effective; however, once in the liver, it is converted by natural chemical processes, hydrolysed hepatically to its active metabolite, the free carboxylate of oseltamivir (GS4071). Oseltamivir phosphate (Tamiflu) serves as a competitive inhibitor towards sialic acid, found on the surface proteins of normal host cells. By blocking the activity of the viral neuraminidase enzyme, oseltamivir phosphate (Tamiflu) prevents new viral particles from being released by infected cells. Oseltamivir phosphate (Tamiflu) is an antiviral compound that slows the spread of influenza (flu) virus between cells in the body by stopping the virus from chemically cutting ties with its host cell.

Product Citations
Chemical Information
Molecular Weight 410.4
Formula C16H28N2O4.H3PO4
CAS Number 204255-11-8
Solubility (25°C) Water 50 mg/mL
DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Glsel Yurtdaş-Kırımlıoğlu, et al. Oseltamivir phosphate loaded pegylated-Eudragit nanoparticles for lung cancer therapy: Characterization, prolonged release, cytotoxicity profile, apoptosis pathways and in vivo anti-angiogenic effect by using CAM assay

[2] Charles W Stratton, et al. Pathogenesis-directed therapy of 2019 novel coronavirus disease

[3] Hila Shaim, et al. Evaluating the effects of oseltamivir phosphate on platelet counts: a retrospective review

[4] Lucie Loukotkov, et al. Pharmacokinetics of oseltamivir phosphate and oseltamivir carboxylate in non-pregnant and pregnant rhesus monkeys

[5] No authors listed. Am J Health Syst Pharm. Oseltamivir phosphate

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Keywords: Oseltamivir phosphate, GS 4104 supplier, Anti-infection, inhibitors, activators

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