Free shipping on all orders over $ 500

Oryzalin

Cat. No. M38935

All AbMole products are for research use only, cannot be used for human consumption.

Oryzalin Structure
Size Price Availability Quantity
50mg USD 40 In stock
100mg USD 60 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Oryzalin is a dinitroaniline herbicide, binding to plant tubulin and inhibits microtubule (MT) polymerization in vitro. Oryzalin depolymerizes MTs and prevented the polymerization of new MTs at all stages of the mitotic cycle.

Chemical Information
Molecular Weight 346.36
Formula C12H18N4O6S
CAS Number 19044-88-3
Form Solid
Solubility (25°C) DMSO 150 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jiyeon Ham et al. Food Chem Toxicol. Oryzalin impairs maternal-fetal interaction during early pregnancy via ROS-mediated P38 MAPK/AKT and OXPHOS downregulation

[2] Rodrigo Aguayo-Ortiz et al. ACS Omega. Unveiling the Possible Oryzalin-Binding Site in the α-Tubulin of Toxoplasma gondii

[3] Lina Baranauskiene et al. J Biochem Mol Toxicol. Herbicide oryzalin inhibits human carbonic anhydrases in vitro

[4] Gihaeng Kang et al. Acta Crystallogr E Crystallogr Commun. Crystal structure of oryzalin

[5] L C Morejohn et al. Planta. Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro

Related Microtubule Products
ABT-751

ABT-751 is an orally bioavailable tubulin inhibitor with IC50 of about 1.5 and 3.4 µM in neuroblastoma and non-neuroblastoma cell lines, respectively.

Vincristine sulfate

Vincristine, formally known as leurocristine, is a mitotic inhibitor used in cancer chemotherapy.

Docetaxel

Docetaxel (Taxotere), a semi-synthetic analog of paclitaxel (Taxol), is a promoter of microtubule polymerization leading to cell cycle arrest at G2/M, apoptosis and cytotoxicity.

Paclitaxel

Paclitaxel is a diterpenoid derived from the bark of the plant Picea abies, and is also a microtubule polymer stabilizer, which promotes polymerization of microtubule proteins to inhibit depolymerization, maintains the stability of microtubule proteins, and inhibits cellular mitosis, and acts on human endothelial cells with an IC50 of 0.1 pM.

Fosbretabulin disodium

Fosbretabulin disodium (Combretastatin A-4 phosphate) is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM.

  Catalog
Abmole Inhibitor Catalog




Keywords: Oryzalin supplier, Microtubule, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.