Free shipping on all orders over $ 500

Oroxin-B

Cat. No. M4462

All AbMole products are for research use only, cannot be used for human consumption.

Oroxin-B Structure
Size Price Availability Quantity
5mg USD 68 In stock
10mg USD 115 In stock
20mg USD 180 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Oroxin B (OB) is a flavonoid isolated from the traditional Chinese herb Oroxylum indicum (L.) Vent. Oroxin B (OB) can inhibit hepatoma cells by up-regulating PTEN, down-regulating COX-2, VEGF, PI3K and P-Akt, and induce early apoptosis. Oroxin B (OB) induces suppressive ER stress in malignant lymphoma cells.

Chemical Information
Molecular Weight 594.52
Formula C27H30O15
CAS Number 114482-86-9
Solubility (25°C) DMSO ≥ 60 mg/mL
Storage 4°C, protect from light, dry, sealed
References

[1] Jun-Ming Huang, et al. Oroxin B Attenuates Ovariectomy-Induced Bone Loss by Suppressing Osteoclast Formation and Activity

[2] Rui Feng, et al. A comprehensive study of the metabolism of flavonoid oroxin B in vivo and in vitro by UHPLC-Q-TOF-MS/MS

[3] Nannan Li, et al. Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer

[4] Kai Niu, et al. Pharmacokinetics and tissue distribution of oroxin B in rats using a validated LC-MS/MS assay

[5] Ping Yang, et al. Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy

Related Apoptosis Products
23-Hydroxybetulinic acid

23-Hydroxybetulinic acid is a novel anticancer substance.

TH-302 (Evofosfamide)

TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM.

Se-Methylselenocysteine

Se-methylselenocysteine, a precursor of methyl selenium, has strong cancer chemoprophylaxis and antioxidant activity. Se-Methylselenocysteine has oral biological activity, can induce apoptosis.

Aloperine

Aloperine is exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.

Ezatiostat

Ezatiostat (TER199, TLK199) is a glutathione analog inhibitor of glutathione S-transferase (GST) P1-1. Ezatiostat leads to JNK activation by inhibiting GSTP1. Ezatiostat stimulates both lymphocyte production and bone marrow progenitor proliferation.

  Catalog
Abmole Inhibitor Catalog




Keywords: Oroxin-B supplier, Apoptosis, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.