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Ophiopogonin D, isolated from the tuber of Ophiopogon japonicus, is a rare naturally occurring C29 steroid glycoside. Ophiopogonin D is a CYP2J3 inducer. By increasing the expression of CYP2J2/EETs and PPARα in human umbilical vein endothelial cells (HUVECs), Ophiopogonin D significantly inhibited Ang Ii-induced NF-κB nuclear translocation and IκBα down-regulation. Intracellular Ca2+ overload and activation of pro-inflammatory cytokines.
| Molecular Weight | 855.02 |
| Formula | C44H70O16 |
| CAS Number | 945619-74-9 |
| Solubility (25°C) | DMSO 80 mg/mL |
| Storage | 4°C, protect from light |
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