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OP-3633 

Cat. No. M29239

All AbMole products are for research use only, cannot be used for human consumption.

OP-3633  Structure

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Quality Control & Documentation
Biological Activity

OP-3633 is a potent and selective steroidal glucocorticoid receptor (GR) antagonist with an IC50 of 29 nM, with inhibition of GR transcriptional activity. OP-3633 exhibits low progesterone receptor (PR) agonism and androgen receptor (AR) antagonism.

Chemical Information
Molecular Weight 445.64
Formula C30H39NO2
CAS Number 2102494-14-2
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Xiaohui Du, et al. J Med Chem. Discovery of a Potent Steroidal Glucocorticoid Receptor Antagonist with Enhanced Selectivity against the Progesterone and Androgen Receptors (OP-3633)

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  Catalog
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Keywords: OP-3633  supplier, GCR, inhibitors, activators

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