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ONO-8711 dicyclohexylamine is a selective and orally active EP1 competitive antagonist with Ki value of 0.6 nM and 1.7 nM for human and mouse EP1 respectively. ONO-8711 dicyclohexylamine effectively reduces tumor incidence and multiplicity in mouse models of colon, breast, and oral cancer.
| Molecular Weight | 621.31 |
| Formula | C34H53ClN2O4S |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL (ultrasonic and warming and heat to 60°C) |
| Storage | 4°C, dry, sealed |
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