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Onalespib lactate is a potent and cross the blood-brain barrier heat-shock-protein-90 (Hsp90) inhibitor with an Kd value of 0.71 nM. Onalespib lactate inhibits the proliferation, survival and migration. Onalespib lactate decreases the expression of EGFR, p-EGFR, AKT, P-AKT, ERK1/2, P-ERK1/2, S6, P-S6 protein. Onalespib lactate shows antitumor activity. Onalespib lactate has the potential for the research of non-small cell lung cancer (NSCLC).
| Molecular Weight | 499.6 |
| Formula | C27H37N3O6 |
| CAS Number | 1019889-35-0 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
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Products are for research use only. Not for human use. We do not sell to patients.
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