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Ombrabulin

Cat. No. M28915

All AbMole products are for research use only, cannot be used for human consumption.

Ombrabulin Structure
Synonym:

AVE8062; AC7700

Price and Availability

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Quality Control & Documentation
Biological Activity

Ombrabulin (AVE8062) is a derivative of CA-4 phosphate, which is known to exhibit antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.

Chemical Information
Molecular Weight 402.44
Formula C21H26N2O6
CAS Number 181816-48-8
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Joachim von Pawel, et al. Lung Cancer. DISRUPT: a randomised phase 2 trial of ombrabulin (AVE8062) plus a taxane-platinum regimen as first-line therapy for metastatic non-small cell lung cancer

[2] Céline Clémenson, et al. Invest New Drugs. The vascular disrupting agent ombrabulin (AVE8062) enhances the efficacy of standard therapies in head and neck squamous cell carcinoma xenograft models

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  Catalog
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Keywords: Ombrabulin, AVE8062; AC7700 supplier, Microtubule, inhibitors, activators

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