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Olorofim

Cat. No. M31108

All AbMole products are for research use only, cannot be used for human consumption.

Olorofim Structure
Size Price Availability Quantity
1mg USD 320 In stock
5mg USD 800 In stock
10mg USD 1100 In stock
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Quality Control & Documentation
Biological Activity

Olorofim is an orally active, novel dihydroorotic acid dehydrogenase inhibitor that also targets pyrimidine biosynthesis in mycobacteria and has antifungal activity.

Chemical Information
Molecular Weight 498.55
Formula C28H27FN6O2
CAS Number 1928707-56-5
Solubility (25°C) DMSO 5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Martin Hoenigl, et al. Drugs. The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin

[2] Esmat Mirbzadeh Ardakani, et al. Antimicrob Agents Chemother. Olorofim Effectively Eradicates Dermatophytes In Vitro and In Vivo

[3] S Seyedmousavi, et al. Antimicrob Agents Chemother. In Vivo Efficacy of Olorofim against Systemic Scedosporiosis and Lomentosporiosis

[4] Nathan P Wiederhold. J Fungi (Basel). Review of the Novel Investigational Antifungal Olorofim

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Keywords: Olorofim supplier, Dehydrogenase, inhibitors, activators

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