All AbMole products are for research use only, cannot be used for human consumption.
ODN 1826 is a class B CpG ODN and an agonist of TLR9, which promotes apoptosis and has antitumor activity. In addition, ODN 1826 induces NO and iNOS production in a mouse model.
| Cell Experiment | |
|---|---|
| Cell lines | Murine RAW264.7 cells and human monocytes |
| Preparation method | Murine RAW264.7 cells or human monocytes were seeded (1 × 10^6 cells/ml, 200 μl/well) in triplicate in 96-well plates and treated with 1 μM CpG-ODN 2216, 1 μM CpG-ODN 1826 or 1 μM CpG-ODN M362. |
| Concentrations | 1 μM |
| Incubation time | 4 h |
| Animal Experiment | |
|---|---|
| Animal models | C57BL/6 mice |
| Formulation | PBS |
| Dosages | 0.1 mg/mice |
| Administration | Intraperitoneal or intravenous injection |
| Molecular Weight | 6364.1 |
| CAS Number | 202668-42-6 |
| Solubility (25°C) | Water 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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