Free shipping on all orders over $ 500

Odevixibat

Cat. No. M10868

All AbMole products are for research use only, cannot be used for human consumption.

Odevixibat Structure
Synonym:

A4250

Size Price Availability Quantity
1mg USD 65 In stock
5mg USD 145 In stock
10mg USD 240 In stock
25mg USD 435 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Odevixibat (A4250) is a potent selective ileal bile acid transporter (IBAT) inhibitor. Odevixibat (A4250) mitigates cholestatic liver and bile duct damage in mouse models. Odevixibat (A4250) can be used in the study of primary biliary cirrhosis.

Chemical Information
Molecular Weight 740.93
Formula C37H48N4O8S2
CAS Number 501692-44-0
Form Solid
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] No authors listed. Med Lett Drugs Ther. Odevixibat (Bylvay) for progressive familial intrahepatic cholestasis-associated pruritus

[2] Emma D Deeks. Drugs. Correction to: Odevixibat: First Approval

[3] Emma D Deeks. Drugs. Odevixibat: First Approval

[4] No authors listed. Am J Health Syst Pharm. Odevixibat Sesquihydrate

[5] Saul J Karpen, et al. Hepatol Int. Ileal bile acid transporter inhibition as an anticholestatic therapeutic target in biliary atresia and other cholestatic disorders

Related Sodium Channel Products
Riluzole

Rilutek is a sodium channel protein inhibitor and a new mental compound, which has anticonvulsant, hypnotic, antianxiety, antiischemia and anesthesia properties. Riluzole belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.

A-803467

A-803467 is a potent and selective Nav1.8 sodium channel blocker that potently blocks tetrodotoxin-resistant currents (IC50 = 140 nM).

Oxcarbazepine

Oxcarbazepine is an anticonvulsant and mood-stabilizing compound.

Ambroxol hydrochloride

AmbroxolHCl is a potent inhibitor of the neuronal Na+ channels, inhibits TTX-resistant Na+ currents with IC50 of 35.2 μM and 22.5 μM for tonic and phasic block, inhibits TTX-sensitive Na+ currents with IC50 of 100 μM.

Camostat mesylate

Camostat mesylate is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.

  Catalog
Abmole Inhibitor Catalog




Keywords: Odevixibat, A4250 supplier, Sodium Channel, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.