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Octreotide is a somatostatin analog that binds to the somatostatin receptor, mainly subtypes 2, 3, and 5, increases Gi activity, and reduces intracellular cAMP production.
*The compound is unstable in solutions, freshly prepared is recommended
| Molecular Weight | 1019.24 |
| Formula | C49H66N10O10S2 |
| CAS Number | 83150-76-9 |
| Solubility (25°C) | Water 90 mg/mL |
| Storage | -20°C, protect from light |
[1] M A Alhasoon. The use of high dose octreotide in management of neonatal chylothorax: Review
[2] Steven W J Lamberts, et al. ANNIVERSARY REVIEW: Octreotide, 40 years later
[3] Eva Murphy, et al. Octreotide
| Related Somatostatin Receptor Products |
|---|
| Pasireotide
Pasireotide is a somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs. |
| Octreotide Acetate
Octreotide acetate(SMS 201995 acetate) is a long-acting octapeptide with pharmacologic actions mimicking those of the natural hormone somatostatin. |
| Cyclosomatostatin acetate
Cyclosomatostatin acetate is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin acetate can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells. |
| FK962
FK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions. |
| Lanreotide
Lanreotide is a somatostatin analogue, acts as an inhibitor of growth hormone (GH). |
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