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Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.
Patent. CA3127892A1 2020 Aug 06.
Patent. CA3127892A1
Oclacitinib maleate purchased from AbMole
| Molecular Weight | 453.51 |
| Formula | C15H23N5O2S.C4H4O4 |
| CAS Number | 1640292-55-2 |
| Solubility (25°C) | 70 mg/mL in DMSO |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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