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Ocaratuzumab

Cat. No. M24562

All AbMole products are for research use only, cannot be used for human consumption.

Ocaratuzumab Structure
Synonym:

AME 133v; LY 2469298; Humanized Anti-MS4A1 Recombinant Antibody

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Quality Control & Documentation
Biological Activity

Ocaratuzumab (AME 133v) is an Fc-engineered humanized IgG1 anti-CD20 monoclonal antibody, with a Kd of ~100 pM. Ocaratuzumab exhibits more effective antibody-dependent cell-mediated cytotoxicity (ADCC).

Chemical Information
CAS Number 1169956-08-4
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Ghid Amhaz, et al. Leuk Res Rep. Immunotherapy in indolent Non-Hodgkin's Lymphoma

[2] Karl R VanDerMeid, et al. Cancer Immunol Res. Cellular Cytotoxicity of Next-Generation CD20 Monoclonal Antibodies

[3] Pawel Robak, et al. Expert Opin Emerg Drugs. Emerging immunological drυgs for chronic lymphocytic leukemia

[4] Carolyn M Cheney, et al. MAbs. Ocaratuzumab, an Fc-engineered antibody demonstrates enhanced antibody-dependent cell-mediated cytotoxicity in chronic lymphocytic leukemia

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Keywords: Ocaratuzumab, AME 133v; LY 2469298; Humanized Anti-MS4A1 Recombinant Antibody supplier, CD20, inhibitors, activators

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