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Obovatol

Cat. No. M10867

All AbMole products are for research use only, cannot be used for human consumption.

Obovatol Structure
Size Price Availability Quantity
5mg USD 360 In stock
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Quality Control & Documentation
Biological Activity

Obovatol, a biphenyl ether lignan isolated from the leaves of Magnolia obovata Thunb, possesses antioxidant, neuroprotective, anti-inflammatory, anti-thrombotic, and antitumor activities. In addition, Obovatol targets the pan-apoptosis (PANoptosis)-related molecule NLRP3/AIM2.

Chemical Information
Molecular Weight 282.33
Formula C18H18O3
CAS Number 83864-78-2
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Van-Tuan Vu, et al. Bioorg Chem. New obovatol trimeric neolignans with NO inhibitory activity from the leaves of Magnolia officinalis var. biloba

[2] Jeongeun Kim, et al. Phytomedicine. Obovatol inhibits NLRP3, AIM2, and non-canonical inflammasome activation

[3] Mingli Duan, et al. Mol Med Rep. Obovatol inhibits the growth and aggressiveness of tongue squamous cell carcinoma through regulation of the EGF‑mediated JAK‑STAT signaling pathway

[4] Heejeong Kim, et al. Phytother Res. Obovatol Induces Apoptosis in Non-small Cell Lung Cancer Cells via C/EBP Homologous Protein Activation

[5] Dong-Young Choi, et al. J Neurochem. Obovatol improves cognitive functions in animal models for Alzheimer's disease

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Keywords: Obovatol supplier, inhibitors, activators

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