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OBI-3424

Cat. No. M21587

All AbMole products are for research use only, cannot be used for human consumption.

OBI-3424 Structure
Synonym:

TH-3424; (R)-Odafosfamide; (R)-AST-3424

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Quality Control & Documentation
Biological Activity

OBI-3424 is a highly selective precursor compound that can be converted into an effective dna alkylating agent by AKR1C3(aldokeone reductase 1C3). It can be used in studies of hepatocellular carcinoma, castration-resistant prostate cancer and acute lymphoblastic leukemia (ALL).

Chemical Information
Molecular Weight 460.42
Formula C21H25N4O6P
CAS Number 2097713-68-1
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage -20℃, protect from light, dry, sealed
References

[1] Kathryn Evans, et al. Clin Cancer Res. OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL

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Keywords: OBI-3424, TH-3424; (R)-Odafosfamide; (R)-AST-3424 supplier, inhibitors, activators

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