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Nvp-adw742 (ADW742) is an orally active, selective igF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. Nvp-adw742 inhibited insulin receptor (InsR) with IC50 of 2.8 μM. Nvp-adw742 induces multipotent anti-proliferation/pro-apoptosis in tumor cells.
| Molecular Weight | 453.58 |
| Formula | C28H31N5O |
| CAS Number | 475488-23-4 |
| Form | Solid |
| Solubility (25°C) | DMSO 22.68 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related IGF-1R Products |
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| PQ401
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