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Nudol

Cat. No. M39161

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Nudol Structure

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Quality Control & Documentation
Biological Activity

Nudol is a phenanthrene compound that has anti-cancer activity. Nudol inhibits cell proliferation, induces cell apoptosis. Nudol inhibits MMP-2M and MMP-9 activity (Ki: 988.9 nM, 1.76 μM, respectively). Nudol can be used in the research of cancers, such as osteosarcoma.

Chemical Information
Molecular Weight 270.28
Formula C16H14O4
CAS Number 86630-46-8
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Yuying Zhang et al. Drug Des Devel Ther. Nudol, a phenanthrene derivative from Dendrobium nobile, induces cell cycle arrest and apoptosis and inhibits migration in osteosarcoma cells

[2] Xian-Jie Ma et al. Zhongguo Zhong Yao Za Zhi. [Chemical constituents from tuber of Bletilla striata]

[3] Ya-Ping Wu et al. Nat Prod Res. Phenolic compounds from the stems of Flickingeria fimbriata

[4] Borbála Réthy et al. Planta Med. Cytotoxic phenanthrenes from the rhizomes of Tamus communis

[5] S Estrada et al. Fitoterapia. Spasmolytic stilbenoids from Maxillaria densa

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  Catalog
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Keywords: Nudol supplier, MMP, inhibitors, activators

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