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NSC-87877 disodium salt

Cat. No. M20614

All AbMole products are for research use only, cannot be used for human consumption.

NSC-87877 disodium salt Structure

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Quality Control & Documentation
Biological Activity

NSC-87877 disodium is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. NSC-87877 disodium also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.

Chemical Information
Molecular Weight 503.42
Formula C19H11N3Na2O7S2
CAS Number 56932-43-5
Solubility (25°C) DMSO 100 mg/mL
Water 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Zongkai Wu, et al. Front Genet. Integrated Analysis of Competitive Endogenous RNA Networks in Acute Ischemic Stroke

[2] Y-Y Xu, et al. Eur Rev Med Pharmacol Sci. PPARγ inhibits breast cancer progression by upregulating PTPRF expression

[3] Pawan Kumar Raghav, et al. PLoS One. Correction: Stem cell factor and NSC87877 combine to enhance c-Kit mediated proliferation of human megakaryoblastic cells

[4] Pawan Kumar Raghav, et al. PLoS One. Stem cell factor and NSC87877 combine to enhance c-Kit mediated proliferation of human megakaryoblastic cells

[5] Pawan Kumar Raghav, et al. Life Sci. Stem cell factor and NSC87877 synergism enhances c-Kit mediated proliferation of human erythroid cells

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  Catalog
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Keywords: NSC-87877 disodium salt supplier, Phosphatase, inhibitors, activators

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