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NSC 668036 is a wnt signaling inhibitor. Binds the PDZ domain of the Dishevelled (Dvl) protein. Inhibits proliferation, migration and TGF-β-induced differentiation of fibroblasts in vitro. Reduces severity of pulmonary fibrosis in a mouse model.
| Molecular Weight | 460.52 |
| Formula | C21H36N2O9 |
| CAS Number | 144678-63-7 |
| Solubility (25°C) | DMSO 46.05 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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