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Nosiheptide

Cat. No. M30300

All AbMole products are for research use only, cannot be used for human consumption.

Nosiheptide Structure
Synonym:

Multhiomycin; RP 9671

Price and Availability

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Quality Control & Documentation
Biological Activity

Nosiheptide (Multhiomycin), a thiopeptide antibiotic produced by Streptomyces actuosus, inhibits bacterial protein synthesis and bears a unique indole side ring system and regiospecific hydroxyl groups on the characteristic macrocyclic core. Nosiheptide has been widely used as a feed additive for animal growth.

Chemical Information
Molecular Weight 1222.36
Formula C51H43N13O12S6
CAS Number 56377-79-8
Form Solid
Solubility (25°C) DMSO 125 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xia Yu, et al. Microbiol Spectr. Nosiheptide Harbors Potent In Vitro and Intracellular Inhbitory Activities against Mycobacterium tuberculosis

[2] Ning Mu, et al. J Nat Prod. Mutasynthesis Generates Antibacterial Benzothiophenic-Containing Nosiheptide Analogues

[3] Jincan Shen, et al. J Chromatogr B Analyt Technol Biomed Life Sci. Direct determination of nosiheptide residue in animal tissues by liquid chromatography-tandem mass spectrometry

[4] K Philip Wojtas, et al. Angew Chem Int Ed Engl. Total Synthesis of Nosiheptide

[5] Q Mo, et al. Lett Appl Microbiol. Enhancing nosiheptide production in Streptomyces actuosus by heterologous expression of haemoprotein from Sinorhizobium meliloti

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Keywords: Nosiheptide, Multhiomycin; RP 9671 supplier, Antibiotic, inhibitors, activators

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