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NNC 63-0532

Cat. No. M7035

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NNC 63-0532 Structure

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Quality Control & Documentation
Biological Activity

NNC 63-0532 is a potent non-peptide agonist for the NOP receptor (EC50 = 305 nM, Ki = 7.3 nM); ~ 12-fold selective over other receptors. Centrally active following systemic administration in vivo.

Chemical Information
Molecular Weight 443.54
Formula C27H29N3O3
CAS Number 250685-44-0
Solubility (25°C) DMSO 22.18 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Willems, et al. Cell Stem Cell. Small molecule-mediated TGF-beta type II receptor degradation promotes cardiomyogenesis in embryonic stem cells.

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Keywords: NNC 63-0532 supplier, Opioid Receptor, inhibitors, activators

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