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NLRP3 Inflammasome Inhibitor I, an intermediate substrate in the synthesis of glyburide which is free of the cyclohexylurea moiety involved in insulin release, is a novel inhibitor of the NLRP3 inflammasome.
| Molecular Weight | 368.84 |
| Formula | C16H17ClN2O4S |
| CAS Number | 16673-34-0 |
| Solubility (25°C) | DMSO 73 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Ayesha Zahid, et al. Front Immunol. Pharmacological Inhibitors of the NLRP3 Inflammasome
[5] Stefano Toldo, et al. Nat Rev Cardiol. The NLRP3 inflammasome in acute myocardial infarction
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