All AbMole products are for research use only, cannot be used for human consumption.
For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.
NLRP3-IN-13 is a potent and selective NLRP3 inhibitor that inhibits NLRP3 and NLRC4 inflammasomes and inhibits NLRP3-mediated IL-1β production with an IC50 value of 2.1 μM. In addition, NLRP3-IN-13 inhibits NLRP3 ATPase activity.NLRP3-IN-13 may be used in the study of neuroinflammation and inflammatory diseases. NLRP3-IN-13 can be used in the study of neuroinflammatory diseases.
| Molecular Weight | 365.41 |
| Formula | C19H15N3O3S |
| CAS Number | 1704638-35-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 50 mg/mL |
| Storage | 4°C, protect from light, dry, sealed |
| Related NLR Products |
|---|
| Nodinitib-1
Nodinitib-1 (ML130) is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM, inhibits NF-κB activation, exhibits 36-fold selectivity over NOD2. |
| Ruscogenin
Ruscogenin is an important steroid saponin extracted from Ophiopogon japonicum. It alleviates blood-brain barrier dysfunction induced by cerebral ischemia by inhibiting TXNIP/NLRP3 inflammatory body activation and MAPK pathway, and has significant anti-inflammatory and antithrombotic activities. |
| Procyanidin-B2
Procyanidin B2 is a natural flavonoid with anti-tumor and anti-oxidation effects. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway. |
| Oridonin
Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity. Oridonin (NSC-250682) also acts as an inhibitor of AKT, with IC50 values of 8.4 and 8.9 μM for AKT1 and AKT2, respectively. |
| Shionone
Shionone, isolated from Aster Tataricus, is a triterpenoid compound with antitussive and anti-inflammatory activities. Shionone has a unique six-membered four-ring framework and a 3-oxygen-4-monomethyl structure. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
