All AbMole products are for research use only, cannot be used for human consumption.
NLG919 is a potent IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM.
Bioact Mater. 2022 Mar 11;16:107-119.
Remodeling tumor immunosuppressive microenvironment via a novel bioactive nanovaccines potentiates the efficacy of cancer immunotherapy
IDO-IN-2 (NLG-919 Analogue) purchased from AbMole
Mol Pharm. 2018 Nov 5;15(11):5162-5173.
Improved Cancer Immunochemotherapy via Optimal Co-delivery of Chemotherapeutic and Immunomodulatory Agents
IDO-IN-2 (NLG-919 Analogue) purchased from AbMole
| Molecular Weight | 282.38 |
| Formula | C18H22N2O |
| CAS Number | 1402836-58-1 |
| Solubility (25°C) | DMSO 56 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related IDO Products |
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| IDO5L
IDO5L is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 67 nM. |
| Coptisine
Coptisine, an alkaloid isolated from Coptis, is an effective non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. |
| Coptisine chloride
Coptisine chloride is an effective and non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. Coptisine chloride is an effective H1N1 neuraminidase (NA-1) inhibitor with IC50 of 104.6 μg/mL, which can be used for influenza A virus (H1N1) infection. |
| Coptisine-Sulfate
Coptisine Sulfate is an alkaloid isolated from coptis coptidis. It is an effective non-competitive IDO inhibitor with Ki value of 5.8 μM and IC50 value of 6.3 μM. |
| Palmatine
Palmatine is an orally active and irreversible IDO-1 inhibitor. Palmatine ameliorates colitis induced by Dextran Sulphate Sodium Salt (DSS) by reducing colon injury, preventing intestinal microbiome imbalance and regulating tryptophan catabolism. Palmatine has potential for colitis research. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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