All AbMole products are for research use only, cannot be used for human consumption.
Nitrofurazone is a topical anti-infective agent with an IC50 of 22.83 ?1.2 uM, and effective against gram-negative and gram-positive bacteria. (Rat LD50 = 590 mg/kg) Nitrofurazone (NF) and its derivative, hydroxymethylnitrofurazone (NFOH), have presented antichagasic activity. In vitro cruzain inhibition tests were performed for both compounds, and the 50% inhibitory concentration (IC50) for NF and NFOH presented values of 22.83 ?1.2 uM and 10.55 ?0.81 uM, respectively. AM1 semi-empirical molecular modeling studies were performed to understand the activity of the compounds, corroborating the observed cruzain inhibitory activity.
| Molecular Weight | 198.14 |
| Formula | C6H6N4O4 |
| CAS Number | 59-87-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 30 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] No authors listed. Med Klin. FURACIN
[2] D R Guay. An update on the role of nitrofurans in the management of urinary tract infections
[3] E Volles, et al. Nitrofural (Furacin) polyneuropathy
[4] H Kala, et al. Therapeutically used 5-nitrofural derivatives. Review of literature. 2
[5] No authors listed. IARC Monogr Eval Carcinog Risks Hum. Nitrofural (nitrofurazone)
| Related Antibiotic Products |
|---|
| Amphotericin B Solubilized
Amphotericin B Solubilized is a powdery form composed of amphotericin sodium deoxycholate and a buffer. This special design enables amphotericin B can be completely dissolved in aqueous solution. |
| Hydroxy Itraconazole
Itraconazole metabolite Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent. |
| Marbofloxacin
Marbofloxacin is a potent antibiotic of the 3rd generation fluoroquinolone group which inhibiting bacterial DNA replication. |
| Linezolid
Linezolid (PNU-100766) is a synthetic antibiotic. Linezolid acts by inhibiting the initiation of bacterial protein synthesis. |
| Daptomycin
Daptomycin is the first member of a new class of bactericidal antibiotics, the cyclic lipopeptides. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
