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Nicotinic Acid

Cat. No. M5812

All AbMole products are for research use only, cannot be used for human consumption.

Nicotinic Acid Structure
Synonym:

Niacin; Vitamin B3

Size Price Availability Quantity
Free Sample (1-2 mg)  USD 0 In stock
500mg USD 40 In stock
1g USD 50 In stock
5g USD 80 In stock
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Quality Control & Documentation
Biological Activity

Nicotinic Acid is a water-soluble vitamin belonging to the vitamin B family. Nicotinic acid (Niacin) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Nicotinic acid (Niacin) is also used in the study of cardiovascular diseases.

Niacin (0-900 μM, 42 hours) significantly increases GSH levels and decreases ROS levels, and affects the expression of genes related to apoptosis and lipid metabolism. Niacin (0-40 μM, 24 hours) can inhibit cancer invasive activity at low dose but with no influence on proliferation.

Niacin (3-300 mg/kg; subcutaneous injection; once) can induce vasodilation in a dose-dependent manner within minutes in male C57BL/6 mice.

Chemical Information
Molecular Weight 123.11
Formula C6H5NO2
CAS Number 59-67-6
Solubility (25°C) DMSO 30 mg/mL
Water 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Tashtoush BM, et al. Pharm Dev Technol. Preparation and characterization of microemulsion formulations of nicotinic acid and its prodrugs for transdermal delivery.

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Keywords: Nicotinic Acid, Niacin; Vitamin B3 supplier, Vitamin, inhibitors, activators

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